Description
JMJD7, also known as JmjC domain-containing protein 7, belongs to the JMJD family. While several JMJD proteins have been identified as being involved in chromatin regulation, histone demethylation and development, the function of JMJD7 has not been identified. It was initially thought to be a novel splice form of the phospholipase PLA2G4B which is located downstream of JMJD7 as most tissues express a read-through transcript of the two genes. Recombinant human JMJD7 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques